Medications Used to Treat MBC

Since my diagnosis, I’ve seen so many different drug names tossed around that it’s hard to keep track. This table is an attempt to organize the ones that I’ve heard of. This is certainly not an exhaustive list and if you find any errors, please let me know. I hope to continually improve and update this table.

Drug nameChemical NameFDA approval for BCTypeBC TypeUsed with
Kisqaliribociclib3/13/17CDK4/6 InhibitorHR+, HER2-Faslodex
Ibrancepalbociclib3/31/17CDK4/6 InhibitorHR+, HER2-aromatase inhibitor
Verzenioabemaciclib9/28/17CDK4/6 InhibitorHR+, HER2-Faslodex
Afinitoreverolimus7/20/12mTOR InhibitorHR+, HER2-Aromasin
Aromasinexemestane10/21/99aromatase inhibitorHR+
Faslodexfulvestrant8/22/2017 (expanded)Estrogen Receptor Downregulators (ERDs)HR+, HER2-
LupronLeuprolideLHRH (luteinizing hormone-releasing hormone) agent hormonal therapypre-menopausal and ER+ or PR+.shut down the ovaries and stop them from producing estrogen; use with tamoxifen or aromatase inhibitor
Zometazoledronic acid2/02commonly for bone metastases
Femaraletrozole1/01aromatase inhibitorER+, PR+,
Zoladexgoserelin acetateLHRH (luteinizing hormone-releasing hormone) agent hormonal therapypre-menopausal and ER+ or PR+.shut down the ovaries and stop them from producing estrogen; use with tamoxifen or aromatase inhibitor
Lapatinib Tykerbkinase inhibitorHER2+
PerjetaPertuzumabmonoclonal antibody HER2+Herceptin
XelodaCapecitabineAntimetabolite chemotherapyTypically it's used to treat metastatic breast cancer that has stopped responding to Taxol, Taxotere, and Adriamycin.
Herceptintrastuzumabmonoclonal antibodyHER2+
Arimidexanastrozole9/1/00aromatase inhibitor
Lynparzaolaparib1/2018PARP inhibitorgermline BRCA mutation, HER2-
TaxolPaclitaxel intravenous infusion