Since my diagnosis, I’ve seen so many different drug names tossed around that it’s hard to keep track. This table is an attempt to organize the ones that I’ve heard of. This is certainly not an exhaustive list and if you find any errors, please let me know. I hope to continually improve and update this table.
Drug name | Chemical Name | FDA approval for BC | Type | BC Type | Used with |
---|---|---|---|---|---|
Kisqali | ribociclib | 3/13/17 | CDK4/6 Inhibitor | HR+, HER2- | Faslodex |
Ibrance | palbociclib | 3/31/17 | CDK4/6 Inhibitor | HR+, HER2- | aromatase inhibitor |
Verzenio | abemaciclib | 9/28/17 | CDK4/6 Inhibitor | HR+, HER2- | Faslodex |
Afinitor | everolimus | 7/20/12 | mTOR Inhibitor | HR+, HER2- | Aromasin |
Aromasin | exemestane | 10/21/99 | aromatase inhibitor | HR+ | |
Faslodex | fulvestrant | 8/22/2017 (expanded) | Estrogen Receptor Downregulators (ERDs) | HR+, HER2- | |
Lupron | Leuprolide | LHRH (luteinizing hormone-releasing hormone) agent hormonal therapy | pre-menopausal and ER+ or PR+. | shut down the ovaries and stop them from producing estrogen; use with tamoxifen or aromatase inhibitor | |
Zometa | zoledronic acid | 2/02 | commonly for bone metastases | ||
Femara | letrozole | 1/01 | aromatase inhibitor | ER+, PR+, | |
Zoladex | goserelin acetate | LHRH (luteinizing hormone-releasing hormone) agent hormonal therapy | pre-menopausal and ER+ or PR+. | shut down the ovaries and stop them from producing estrogen; use with tamoxifen or aromatase inhibitor | |
Lapatinib | Tykerb | kinase inhibitor | HER2+ | ||
Perjeta | Pertuzumab | monoclonal antibody | HER2+ | Herceptin | |
Xeloda | Capecitabine | Antimetabolite chemotherapy | Typically it's used to treat metastatic breast cancer that has stopped responding to Taxol, Taxotere, and Adriamycin. | ||
Herceptin | trastuzumab | monoclonal antibody | HER2+ | ||
Arimidex | anastrozole | 9/1/00 | aromatase inhibitor | ||
Lynparza | olaparib | 1/2018 | PARP inhibitor | germline BRCA mutation, HER2- | |
Taxol | Paclitaxel | intravenous infusion |